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Citing limitations in the study, Novo Nordisk, which makes the drugs included in the claims analysis, said in a statement reported by Reuters that it does not believe these data are sufficient to draw conclusions about overall patient adherence and persistence to various GLP-1 medicines, including our treatments. Nonetheless, the problem of lack of patient persistence on GLP-1s under real-world conditions, examined and published by a growing number of sources, isnt going away
Cleavable Linkers Cleavable linkers depend on intracellular processes to release cytotoxic molecules, including the reduction in the cytoplasm, exposure of the target to the lysosome, or cleavage by specific intracellular proteases
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