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Hyperhomocysteinemia: An independent risk factor for vascular disease

So researchers looked at the medical records of more than 3,000 people with hormone receptor-positive DCIS on hormonal therapy and GLP-1s, as well as an equal number of people with hormone receptor-positive DCIS who were not taking GLP-1s

The most frequently reported adverse effects are gastrointestinal: nausea, vomiting, and diarrhea, which in published RCTs often occurred at rates similar to or only modestly above placebo