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Thanks for helping to unravel it seems we have some things in common which is why I asked
Joshi NC, Meyer AJ, Bangash SAK, Zheng Z-L, Leustek T (2018) Arabidopsis -glutamylcyclotransferase affects glutathione content and root system architecture during sulfur starvation
Transfection of Cyp2E1 [145] or induction of Cyp2E1 by dimethyl sulfoxide (DMSO) [139], can restore at least in part the metabolic capacity of HepG2 cells but the overall gene expression profile of HepG2 cells shows low similarity to primary human hepatocytes [146, 147]
This was revealed through analysis using the Broad Institute's Connectivity Map, a database of gene expression responses to known compounds
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