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Its primary roles include: Stimulating insulin secretion Inhibiting glucagon release Slowing gastric emptying Reducing appetite via central pathways While most known triggers of GLP-1 release are nutrientsespecially fats and carbohydratesrecent research suggests that immune and microbial signals may also stimulate L-cell activity

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In nucleated cells, apoptosis and necroptosis dont occur simultaneously, with each inhibiting the other one [26]