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It should be used as advised by a healthcare professional, and excessive supplementation should be avoided

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However, future prospective randomized, controlled trials are needed to explore the role of natural bioactive compounds as well as their supplements on health status, lung function and risk of COPD development

Moreover, treatment of CC mice with NA rescued NAD + levels in skeletal muscle, improved muscle function, and increased Oxphos complexes expression, yet NA treatment had no effect on mitochondrial respiration 248