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Peptides 2013;44:7586

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The attached gingiva is the most common location, but physiological pigmentation can be noted anywhere in the oral cavity, including the tips of the fungiform papillae on the dorsal tongue and the diagnosis of physiological pigmentation normally is made clinically and do not need any treatment (4)

And so in that way, we may be able to use GLP ones to alter the lesions, actual hormone receptors, because if they're not resistant, they're not gonna upregulate estrogen receptors as much