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ASPL is required for efficient VCP-mediated extraction of G3BP from SGs Our studies demonstrating interactions between ASPL and VCP hexamers and between recombinant ASPL and G3BP, combined with our unbiased proteomics data suggesting that ASPL stabilizes the G3BP-VCP interaction in stressed cells, led us to hypothesize that ASPL helps catalyze the extraction of G3BP by VCP

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Discussion Recently, the National Health Commission of China has established reference intervals for various laboratory indicators through multicenter studies, offering valuable insights into their clinical applications [19, 20]

PLoS One 10, e0121257