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24 In this study, we have demonstrated that both GSSG and GSH exerted their effects on melanin indices, which reached statistically significant levels at specific site and higher age group

It lightens gradually, but maintenance is needed to sustain results

Notably, large meta-analyses and collaborative trial datasets have demonstrated no excess risk of severe hypoglycemia, major adverse events, or treatment discontinuation with combination therapy compared with either class alone [11, 28,29,30], supporting the safety and tolerability of combined use in diverse populations

A reduction in fat and weight was also observed (141)