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Description

The cells were collected by centrifugation at 2000 g for 5 min and washed in phosphate buffered saline (8 gL 1 NaCl, 0.2 gL 1 KCl, 1.44 gL 1 Na 2 PO 4 , 0.24 g L 1 KH 2 PO 4 , at pH 7.5)

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When NAD+ levels are adequate, SIRT1 activity increases, promoting DNA repair, reducing inflammation, and enhancing stress resistance

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Moreover, the increased morbidity and mortality in patients with NASH is known to be closely related to the severity of liver fibrosis

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Because of its stable format, it also supports consistent testing conditions in many laboratory models

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