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the decrease in HGF-dependent MDCK proliferation below control levels for some compounds is not surprising since the experiment was earned in 2% serum, which likely contains some level of HGF

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HESI ion source parameters were as follows: sheath gas 50, aux gas 20 and sweep gas 2 arbitrary units, spray voltage was set to 4.0 kV, capillary temperature to 300 C, S-Lens RF level to 50 and auxiliary gas heater temperature to 120 C