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A focused gastrointestinal review should ask about nausea, vomiting, abdominal distension, reflux, early satiety, constipation, postprandial fullness, and prior gastroparesis

Fernndez-Ruiz J, Berrendero F, Hernndez ML, Ramos JA

Specifically, in the extracellular half of GLP-2R, TM1 forms at least one additional helical turn, thereby moving toward TM2 (5 , measured by C of the residue at 1.33b) and bending down toward GLP-2