glp-1 agonist drugs oral GLP‑1 Therapy Type 2 Diabetes: A Game-Changer Medication Options for Type 2

Collectively, these data reveal that exendin 2029 acts as a key sequence in inducing analgesia in CAP-elicited nociceptive behaviors in mice without causing hyperthermia, and this analgesic effect is mediated by exendin 2029 directly inhibiting CAP-induced TRPV1 activation but not proton-induced TRPV1 activation

e-pub ahead of print 26 September 2014

The most common side effects are gastrointestinal: nausea, vomiting, diarrhea, and constipation, particularly during the dose escalation phase when your body is adjusting to the medication

Metabolic Changes: As your metabolism shifts, especially if youre losing weight and adjusting your diet, your body can react in unpredictable ways, including sweating more than usual