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Adolescents were mostly prescribed GLP-1 receptor agonists by endocrinologists (32.7%), whereas young adults were mostly prescribed GLP-1s by nurse practitioners (33%)

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The first attempt at oral insulin was in 1922, one year after insulins discovery

Moreover, alterations in the gut microbiota as described in mice require careful analysis in human studies including the assessment of a possible growth advantage for pathogenic bacteria as part of a commensal microbiome or with respect to systemic effects and clinical relevance