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There is a next generation of GLP-1 agonists being developed that may preserve weight loss even after the medication is stopped, which would impact how the medication is used in the long term 5

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Some people may notice indirect improvements in energy levels, bloating, mobility, or overall comfort during treatment, although responses can vary significantly between individuals

Side Effects of Tirzepatide GLP-1 drugs like Zepbound have recently risen in popularity in the U.S