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Chronic pain affects approximately 20% of the human population 42 and is recognized as a maladaptive condition involving central mechanisms 43,44,45,46,47

Include natural laxative foods : Prunes, kiwifruit, flaxseeds, and psyllium husk can promote regular bowel movements

Their benefits come with a complex and often under appreciated constellation of adverse effects, some of which are expected, some emerging, and some still poorly understood. Conclusion: GLP-1 RAs exemplify a fundamental principle in contemporary medicine: with every advantage comes a potential drawback

Funduscopy revealed optic disc edema with the presence of small splinter hemorrhages