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The STEP-1 trial found mean body weight reduction of 14.9% at 68 weeks, but individual response varies based on baseline BMI, dietary structure, and adherence to dose escalation

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Effect of GLP-1 receptor agonists on body composition

A lower court dismissed the claims based on a state statute that allows for weight-loss drugs to be medicine that health plans are "not required to include." In the binding appeals court ruling, judge Ian Birk determined the regulation establishes a minimum benefit and does not address whether the exclusion is discriminatory