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PAR2-G37I and PAR2-R38E mice on a normal chow diet (NCD) showed no differences in body weight, fasting glucose, and insulin levels compared with WT mice (Supplemental Figure 5, AC)

To reduce symptoms, patients can try eating smaller meals throughout the day, avoiding high-fat or fried foods, and drinking plenty of water

doi: 10.3389/fendo.2017.00098 Received 18 January 2017 Accepted 18 April 2017 Published 03 May 2017 Volume 8 - 2017 Edited by Maria Felicia Faienza, Universit degli studi di Bari Aldo Moro, Italy Reviewed by Jameela Banu, University of Texas Rio Grande Valley, USA

Even more concerning is the rise in severe obesity