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Speak with a provider first if you have: A history of cancer or active malignancy Uncontrolled diabetes or blood sugar concerns Severe swelling or fluid retention Sleep apnea or breathing concerns Significant heart, kidney, or liver disease Pregnancy, breastfeeding, or pregnancy plans Severe headaches or vision changes Current hormone-related treatment A history of allergic reactions to injections Unverified peptide products purchased online A provider can help decide whether Ipamorelin is appropriate, whether lab review is needed, and whether another peptide therapy option may be safer