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Moreover, due to its beneficial effects on liver health, glutathione is commonly used as a supplementary treatment for conditions such as alcoholic fatty liver, alcoholic liver fibrosis, alcoholic liver cirrhosis, and alcoholic hepatitis

reported that LKB1 mutation in KRAS mutant lung adenocarcinoma confers a glutamate enriched phenotype in TME, and this feature was associated with CD8 + T cell activation against PD-1, whereas treatment with the glutaminase inhibitor CB-839 inhibited CD8 + T cell expansion and activation

10.1016/j.jff.2018.06.011 108 LiuC.WangW.LiH.LiuJ.ZhangP.ChengY.et al (2021)

Furthermore, subjects with the lowest GSB levels were those with CD4+ T cell counts below 200 cells/mm 3