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Thus, impaired CCK signaling in HFD-induced obesity may be due to increased LPS-driven leptin resistance at VANs

Comorbidities such as cardiovascular disease, sleep apnea, or uncontrolled diabetes change priorities: reduce hypoglycemia risk, avoid volume depletion, and maintain glycemic targets that fit the procedures risk profile

Mutation of cysteine 26 alone or in combination with mutation of other cysteines increases GLRX deglutathionylation activity We next investigated the deglutathionylating activity of WT GLRX or GLRX Cys-Ser mutants using diE-GSSG (Fig