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While exendin-4 triggered a similar degree of mitochondrial network remodelling as above in Control RNAi-treated cells, SPHKAP knockdown resulted in disrupted mitochondrial morphology at vehicle conditions, which somewhat resembled that of exendin-4-stimulated Control RNAi-treated cells in terms of tubularity but had further visual abnormalities

Parkinson disease , in StatPearls treasure (Island, FL: StatPearls Publishing)

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Data derived from a retrospective survey of 245 patients with IBD suggest that the prevalence of bone fractures in people with ulcerative colitis and Crohns disease is unexpectedly high, particularly in patients who have a long duration of disease, frequent active phases, and high cumulative doses of glucocorticoid intake (Miheller 2010