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Gallbladder and biliary disease Several meta-analyses have found that GLP-1 agonists carry a modest increase in the risk of gallbladder or biliary disease (such as gallstones and cholecystitis), especially at higher doses, over longer durations, and when used mainly for weight loss [3]

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Similarly, in other animal investigations, increased MDA has been reported in riboflavin-deficient animals which decreased following riboflavin administration (Reference Jiang, Chen and Liu33Reference Tang, Wen and Guo36)