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Hydroxocobalamin is widely recognized for its stability and sustained activity compared to other forms of cobalamin

Preclinical studies have showed that PDE inhibitors, such as sildenafil and cilostazol, can decrease tissue pathology, accelerate bacterial clearance, and reduce the time to lung sterilization in M.tb -infected mice when used in combination with standard TB therapy [33]

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Glucose-6-phosphate dehydrogenase is found in all cells and is responsible for the first reaction of the pentose phosphate pathway in which glucose-6-phosphate is oxidized to 6-phosphogluconolactone with concomitant production of NADPH