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Atractylenolide I can enhance Lactobacillus and Bacteroides , reduces the levels of Escherichia and Candidatus , and by suppressing the TLR4/MyD88/NF-B pathway to reduce IL-1 and LPS levels ( Actinobacteria growth, elevates Bacteroidetes levels ( In summary, Atractylodes macrocephala Koidz can modulate inflammatory responses and oxidative stress, reduce harmful intestinal bacteria, and increase beneficial bacteria

Aromatase inhibitors, which inhibit local estrogen synthesis in endometriotic tissue and can reduce pain, are recommended only for resistant cases in combination with other hormonal agents due to adverse effects and limited clinical data

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Dr Fitzgerald