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"For those of us who are in the field, we think this is part of how these medications are working." The drugs also appear to alter what is referred to as the body's "defended fat mass set point," Jastreboff said

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One patient shared, After 18 months, I tweaked my fitness routinenow Ive kept off 35 pounds for three years. Celebrate Milestones Acknowledge non-scale wins (e.g., hiking stamina, reduced medication needs) to stay motivated