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The target sample size was approximately 1,500 women per study, with the goal of enrolling around 550 women for randomization, and collecting over two months of data from at least 450 women during the double-blind treatment phase

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One of our members, Rachel (42), took a 3-month break to save for a family move

However, the cardiovascular effects of these metabolites require evaluation in the context of host metabolic status, as some oxysterols may exert protective effects through anti-inflammatory mechanisms, while overall dysbiosis of gut microbial metabolic activity may drive harmful metabolite accumulation (Li et al., 2024)