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Typically, a series of injections is administered over several weeks or months

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doi: 10.3389/fphar.2018.00453 Received 28 February 2018 Accepted 18 April 2018 Published 15 May 2018 Volume 9 - 2018 Edited by Nabil Eid, Osaka Medical College, Japan Reviewed by Hartmut Jaeschke, University of Kansas Medical Center, United States

It is naturally produced by the body, but levels may vary due to lifestyle, environmental exposure, and metabolic demands