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The PINK1 p.I368N mutation affects protein stability and ubiquitin kinase activity

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Specifically, the methylation site cq21325723 (chr6:32,402,555) mediates the interaction between the SNP rs6933349 (chr6:31,002,013) and smoking, contributing to the risk of developing anti-citrulline peptide antibody (ACPA)-positive RA [39]

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