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483 DOX-induced cardiomyopathy results in myocardial autophagy dysfunction, accumulation of iron in both cell and mitochondria, and elevated levels of ROS, 4-HNE, and MDA

[23] concluded that allicin effectively ameliorated vascular and cardiac remodelling induced by hypertension through inhibition of the CaMKII/NF-B signalling pathway, reduction in serum levels of IL-1, IL-6, and TNF-, improvement in calcium homeostasis in cardiomyocytes, and downregulation of the NLRP3 inflammasome

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