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That showed basically binding of either dynorphin or whatever ligand to the kappa opioid receptor, basically sensitizes the Mu opioid receptor to the feel-good endorphins, and also changes

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We are thankful for the technical services provided by the Transgenic Mouse Models Core Facility of the National Core Facility for Biopharmaceuticals, National Science and Technology Council, Taiwan, as well as the Gene Knockout Mouse Core Laboratory of the National Taiwan University Center of Genomic and Precision Medicine