glp-1 agonists and sglt2 inhibitors Mechanisms underlying favorable effects of GLP-1R Use of GLP-1 Receptor Agonists

Berg U, Bang P

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Microdosing GLP-1s, like Ozempic or Wegovy, has exploded in popularity over the past year with some TikTok creators saying it has completely changed their lives. Some are microdosing as a way to maintain weight, while others are using it as a cost-cutting method

Future studies are needed to compare the clinical impact of GLP-1RA, in terms of NNT, with other therapies in the pipeline that target the various pathways in the ASCVD process, such as bempedoic acid which has been associated with reduced risk of MI and coronary revascularization due to the improvement in lipid and inflammatory profiles [77]