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Our results demonstrate that GLP-1 protein is synthesized in the NTS of mice, whereas the BLA expresses the GLP-1R and receives GLP-1 projections, thereby confirming the presence of a neural circuit between these brain regions and highlighting the role of the GLP-1 signaling pathway [20,55]

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Furthermore, long-term studies should be designed to evaluate the chronic impacts of phytochemical interventions on the progression of IC and the quality of life for patients

Traumatic brain injuries can elicit a similar response in wild-type mice, causing elevated plasma cortisol levels and decreased circulating T cell populations, suggesting that the brain can regulate immune responses through the HPA axis [289]