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Making Your Final Decision Both Zepbound and Wegovy represent major advances in obesity treatment, producing weight loss results that seemed impossible just a few years ago

Semaglutide's weight loss effects come from its action on GLP-1 receptors in the brain and gut

Over the past two decades, a greater understanding of the complex and multifactorial pathogenesis of T2D has resulted in the development and introduction of new-generation classes of glucose-lowering therapies, which are now extensively endorsed by prevailing guidelines and are increasingly being used worldwide

Eligible studies were published between 2014-2024 (Figure 2)