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AEDG peptide and histones H1/3, H1/6 binding may be one of the mechanisms which provides an increase of Nestin, GAP43, Tubulin III, and Doublecortin neuronal differentiation gene transcription

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Furthermore, low vitamin D levels in pregnant women are associated with an increased risk of fatal asthma, preeclampsia, gestational diabetes, preterm births, low birth weight wheeze, respiratory tract infections, and eczema [110, 111, 115,116,117]

Also, unlike therapies that are used to treat blood pressure or cholesterol, the perception that these are not chronic disease therapies may also be contributing