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For example, Topamax at doses of 200mg daily or higher can reduce the effectiveness of combined hormonal contraceptives, and women of childbearing potential must use highly effective contraception as part of the Pregnancy Prevention Programme

The most common side effects with these GLP-1 type medicines are stomach-related and may include nausea, diarrhea, vomiting, constipation, stomach pain, heartburn, burping, and reduced appetite

& Lushchak, O