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If symptoms such as muscle weakness arise, patients should promptly consult their healthcare provider for proper evaluation and management

Tirzepatide Tirzepatide is a dual GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptor agonist sometimes called a twincretin. GIP is a second gut hormone involved in insulin secretion, fat storage regulation, and energy metabolism

However, the GI side effects (particularly vomiting and diarrhea) can cause dehydration, which hits people with existing kidney disease much harder

At the moment, patients can only receive Semaglutide on the NHS via Tier 3 weight loss clinics, and then only for 2 years