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Wangikar, P

Replacing the sulfonic acid at position R 1 with a sulfonamide group ( 33 ) resulted in a drastic decrease in solubility of the fragment with a concomitant reduction of binding to TRF1 TRFH by CPMG, whilst the dimethyl sulfonamide 35 or the even bigger benzyl sulfonamide 36 showed an even poorer solubility and a loss of TRF1 TRFH binding (Table 1)

Its important to know how they might interact with other medicines

When stored at these temperatures, unopened tirzepatide remains stable for the duration specified on your medication label, typically up to 36 months depending on the compounding pharmacy's formulation