Cytokine production and serum proteins in depression
Charles W
Curr Neurovasc Res 18(1):134149 Marchetti C, Swartzwelter B, Gamboni F, Neff CP, Richter K, Azam T, Carta S, Tengesdal I, Nemkov T, D'Alessandro A, Henry C, Jones GS, Goodrich SA, St Laurent JP, Jones TM, Scribner CL, Barrow RB, Altman RD, Skouras DB, Gattorno M, Grau V, Janciauskiene S, Rubartelli A, Joosten LAB, Dinarello CA (2018) OLT1177, a -sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation
The common adverse effects include mild, transient headaches, and skin eruptions ranging from mild to severe drug reactions such as fatal StevensJohnson syndrome and toxic epidermal necrolysis, kidney and liver dysfunction, thyroid dysfunction, severe abdominal pain, and fatal complications such as air embolism or sepsis due to incorrect method of IV administration.[] TOPICAL FORMULATIONS Topical formulations of glutathione are also available in the form of cream, facewash, soap, and lotion