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Plumbagin increased NAD(P)H quinone dehydrogenase 1 (NQO1) activity and decreased xCT expression, resulting in NQO1-dependent glioma cell death
134,135 In MASLD, high-fat diet-induced oxidative stress and the release of inflammatory cytokines (such as TNF-) directly downregulate the transcription and translation of tight junction proteins by activating signaling pathways like NF-B
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The gallbladder is not an essential organ, which means you can live normally without a gallbladder
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