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3 Normal cardiac energy metabolism and abnormal cardiac energy metabolism 3.1 Energy metabolism of the normal heart Under normal physiological conditions, the heart generates adenosine triphosphate (ATP) through mitochondrial oxidative phosphorylation, utilizing fatty acids oxidation (FAO), glucose, lactic acid, ketone bodies, and amino acids (AA) (34, 35)

As research continues to unfold, the role of semaglutide in treating insulin resistance becomes increasingly clearer, signaling hope for those striving to regain control over their metabolic health