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The flexible nature of IDPs and IDRs makes them particularly susceptible to a wide range of PTMs (Dunker et al., 2002
Lyophilized versus reconstituted stability The physical state of a peptide dramatically influences its room temperature stability
H. Penget al., Thymosin-4prevents cardiac rupture and improves cardiac function in mice with myocardial infarction, American Physiological Society, Sep. 2014. doi: 10.1152/ajpheart.00129.2014
Additionally, in the acute lung injury model, significantly upregulating the expression of FXR can inhibit the phosphorylation of p38 MAPK and NF-B p65, reduce the release of inflammatory factors, and thereby protect lung tissue (108)
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