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Role of matrix metalloproteinase 3-mediated alpha-synuclein cleavage in dopaminergic cell death

According to recommendations from nutrition institutes and the World Health Organization (WHO), the daily Recommended Dietary Allowance (RDA) is as follows: Infants 06 months: 0.4 mcg Infants 712 months: 0.5 mcg Children 13 years: 0.9 mcg Children 48 years: 1.2 mcg Children 913 years: 1.8 mcg Teenagers 14+ years and adults: 2.4 mcg Pregnant women: 2.6 mcg Breastfeeding women: 2.8 mcg Receiving adequate daily Vitamin B12 helps reduce the risk of anemia, fatigue, and neurological problems, while supporting optimal metabolic and overall bodily function

A B12 deficiency can lead to anemia, which reduces the oxygen-carrying capacity of the blood, resulting in fatigue, weakness, and shortness of breath

However, the differences are minimal and the clinical relevance is unknown