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Leptin did not impact the kinetics of glutamate signaling, as there were no differences measured in the rise and decay times of averaged mEPSC events normalized to peak current in GLP-1 R-Cre::tdTom::WT controls and GLP-1 R-Cre::tdTom::Lep ob/ob mice (Figure 6G)

All the compounds in Family one were tested using the c-Met phosphorylation assay

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Decreases body fat: Ipamorelin appears to speed up the growth hormone levels necessary for lipolysis, which is the process by which fats are broken down in our bodies through enzymes and water, or hydrolysis [6]