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Omeprazole is primarily metabolised in the liver by cytochrome P450 enzymes (mainly CYP2C19 and CYP3A4), whilst Wegovy, being a peptide-based medication, is broken down by proteolytic enzymes into smaller peptides and amino acids

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Glycyrrhetinic acid alleviates hepatic inflammation injury in viral hepatitis disease via a HMGB1-TLR4 signaling pathway

Older insulin secretagogues and DPP-4 inhibitors work through narrower pathways and carry higher hypoglycemia risk, while tirzepatide's mechanism is less likely to cause dangerously low blood sugar when used appropriately