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Some participants withdrew from the 12 mg arm because they could not tolerate the escalation, whereas most completed the 4 mg and 8 mg dose levels

Int J Mol Sci 24(8):6992

Research Note: Due to pH sensitivity and stability, IGF-1 LR3 is commonly handled separately in laboratory preparation workflows

The results were presented at the American Heart Association Scientific Sessions 2025, and the article was published as an Accelerated Article Preview in Nature Medicine on November 9, 2025