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A 2024 retrospective chart review found that 67% of IBS-D (diarrhea-predominant) patients using GLP-1 medications reported moderate to significant symptom improvement within 812 weeks of starting treatment

Specifically, SIRT3 deacetylates and inhibits aldehyde dehydrogenase 2, which prevents the conversion of acetaldehyde to acetate, potentially leading to acetaldehyde toxicity 183

Sleep Hygiene and GLP-1 Medications: A Connection Worth Noting While lifestyle factors such as stress, diet, and activity levels are often at the forefront of sleep conversations, certain medications can also play a role in influencing sleep patterns

Colantonio then has monthly check-ins with patients to track their progress