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More recently, mGPDHs protective function was validated in vivo: in a mouse model of sepsis-induced acute lung injury, mGPDH knockdown exacerbated lung injury, vascular leakage, inflammation and oxidative damage, accompanied by elevated ferroptotic markers 100

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Yatsunenko, T

Small molecule, BIG impact: how glutathione metabolism affects fungal virulence via redox regulation Published in Microbiology India Ambler Being a pathogen is no easy task it requires the exquisite coordination of attack and defense systems that protect the pathogen from the harsh host environment and help facilitate infection