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However, KYNA influences AMPAR activity predominantly through indirect mechanisms, namely its non-competitive allosteric inhibition of presynaptic 7nAChRs on glutamatergic terminals in mood-related circuits, leading to reduced glutamate release and downstream modulation of excitatory signalling [29, 30]

A three-quarter mile boardwalk winds through three of the wetlands ponds, allowing visitors the opportunity to read interpretive signs and learn about water purification, wetlands ecology, natural history, and the interdependance of people and their environment