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Furthermore, the degree to which various exogenous GLP1-RAs penetrate the bloodbrain barrier (BBB) and access central receptors remains unresolved and an ongoing area of research

65 However, this value represents the minimum amount needed to prevent deficiency in the general sedentary population, not necessarily the optimal amount for active individuals, older adults, or those undergoing weight loss

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Inflammopharmacology (2022) 30(3):104762