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Persistent hunger throughout the day, no change in food noise or cravings, and no weight loss after 4 or more weeks on a stable dose all suggest the dose is too low or absorption is insufficient

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It acts on the brain and reduces and suppresses appetite, it acts on the GI system to kind of slow the emptying so a person tends to feel fuller and tends to eat less as a result, and it also acts on the pancreas to stimulate insulin release when the patient is eating, Vennelaganti said